@article{Chen-2018-Perfluorobutanesulfonate,
title = "Perfluorobutanesulfonate Exposure Causes Durable and Transgenerational Dysbiosis of Gut Microbiota in Marine Medaka",
author = "Chen, Lianguo and
Lam, James C.W. and
Hu, Chenyan and
Tsui, Mirabelle M.P. and
Wang, Qi and
Giesy, John P. and
Lam, Paul K.S.",
journal = "Environmental Science {\&} Technology Letters, Volume 5, Issue 12",
volume = "5",
number = "12",
year = "2018",
publisher = "American Chemical Society (ACS)",
url = "https://gwf-uwaterloo.github.io/gwf-publications/G18-29001",
doi = "10.1021/acs.estlett.8b00597",
pages = "731--738",
abstract = "Environmental pollutants are known as disruptors of gut microbiota. However, it remains unexplored whether the dysbiosis of gut microbiota by pollutants is durable and transgenerational in teleost. Therefore, this study exposed eggs of marine medaka to environmentally realistic concentrations (0, 1.0, 2.9, or 9.5 μg/L) of perfluorobutanesulfonate (PFBS), a persistent organic pollutant of emerging concern, until sexual maturity. A proportion of F0 adults was dissected after exposure (F0-exposed). Remaining fish were depurated in clean seawater (F0-depurated). F1 offspring were also cultured in clean seawater for a complete life-cycle. Substantial amounts of PFBS were accumulated in F0-exposed intestines, while F1 intestines contained no PFBS. Significant alterations were observed in physiological activities of F0-exposed and F1 medaka. The gut microbial community in F0-exposed, F0-depurated, and F1 medaka were restructured in a concentration-dependent manner by PFBS exposure. Dysbiosis of gut microbiota ca...",
}
<?xml version="1.0" encoding="UTF-8"?>
<modsCollection xmlns="http://www.loc.gov/mods/v3">
<mods ID="Chen-2018-Perfluorobutanesulfonate">
<titleInfo>
<title>Perfluorobutanesulfonate Exposure Causes Durable and Transgenerational Dysbiosis of Gut Microbiota in Marine Medaka</title>
</titleInfo>
<name type="personal">
<namePart type="given">Lianguo</namePart>
<namePart type="family">Chen</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">James</namePart>
<namePart type="given">C.W.</namePart>
<namePart type="family">Lam</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Chenyan</namePart>
<namePart type="family">Hu</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Mirabelle</namePart>
<namePart type="given">M.P.</namePart>
<namePart type="family">Tsui</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Qi</namePart>
<namePart type="family">Wang</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">John</namePart>
<namePart type="given">P</namePart>
<namePart type="family">Giesy</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Paul</namePart>
<namePart type="given">K.S.</namePart>
<namePart type="family">Lam</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<originInfo>
<dateIssued>2018</dateIssued>
</originInfo>
<typeOfResource>text</typeOfResource>
<genre authority="bibutilsgt">journal article</genre>
<relatedItem type="host">
<titleInfo>
<title>Environmental Science & Technology Letters, Volume 5, Issue 12</title>
</titleInfo>
<originInfo>
<issuance>continuing</issuance>
<publisher>American Chemical Society (ACS)</publisher>
</originInfo>
<genre authority="marcgt">periodical</genre>
<genre authority="bibutilsgt">academic journal</genre>
</relatedItem>
<abstract>Environmental pollutants are known as disruptors of gut microbiota. However, it remains unexplored whether the dysbiosis of gut microbiota by pollutants is durable and transgenerational in teleost. Therefore, this study exposed eggs of marine medaka to environmentally realistic concentrations (0, 1.0, 2.9, or 9.5 μg/L) of perfluorobutanesulfonate (PFBS), a persistent organic pollutant of emerging concern, until sexual maturity. A proportion of F0 adults was dissected after exposure (F0-exposed). Remaining fish were depurated in clean seawater (F0-depurated). F1 offspring were also cultured in clean seawater for a complete life-cycle. Substantial amounts of PFBS were accumulated in F0-exposed intestines, while F1 intestines contained no PFBS. Significant alterations were observed in physiological activities of F0-exposed and F1 medaka. The gut microbial community in F0-exposed, F0-depurated, and F1 medaka were restructured in a concentration-dependent manner by PFBS exposure. Dysbiosis of gut microbiota ca...</abstract>
<identifier type="citekey">Chen-2018-Perfluorobutanesulfonate</identifier>
<identifier type="doi">10.1021/acs.estlett.8b00597</identifier>
<location>
<url>https://gwf-uwaterloo.github.io/gwf-publications/G18-29001</url>
</location>
<part>
<date>2018</date>
<detail type="volume"><number>5</number></detail>
<detail type="issue"><number>12</number></detail>
<extent unit="page">
<start>731</start>
<end>738</end>
</extent>
</part>
</mods>
</modsCollection>
%0 Journal Article
%T Perfluorobutanesulfonate Exposure Causes Durable and Transgenerational Dysbiosis of Gut Microbiota in Marine Medaka
%A Chen, Lianguo
%A Lam, James C.W.
%A Hu, Chenyan
%A Tsui, Mirabelle M.P.
%A Wang, Qi
%A Giesy, John P.
%A Lam, Paul K.S.
%J Environmental Science & Technology Letters, Volume 5, Issue 12
%D 2018
%V 5
%N 12
%I American Chemical Society (ACS)
%F Chen-2018-Perfluorobutanesulfonate
%X Environmental pollutants are known as disruptors of gut microbiota. However, it remains unexplored whether the dysbiosis of gut microbiota by pollutants is durable and transgenerational in teleost. Therefore, this study exposed eggs of marine medaka to environmentally realistic concentrations (0, 1.0, 2.9, or 9.5 μg/L) of perfluorobutanesulfonate (PFBS), a persistent organic pollutant of emerging concern, until sexual maturity. A proportion of F0 adults was dissected after exposure (F0-exposed). Remaining fish were depurated in clean seawater (F0-depurated). F1 offspring were also cultured in clean seawater for a complete life-cycle. Substantial amounts of PFBS were accumulated in F0-exposed intestines, while F1 intestines contained no PFBS. Significant alterations were observed in physiological activities of F0-exposed and F1 medaka. The gut microbial community in F0-exposed, F0-depurated, and F1 medaka were restructured in a concentration-dependent manner by PFBS exposure. Dysbiosis of gut microbiota ca...
%R 10.1021/acs.estlett.8b00597
%U https://gwf-uwaterloo.github.io/gwf-publications/G18-29001
%U https://doi.org/10.1021/acs.estlett.8b00597
%P 731-738
Markdown (Informal)
[Perfluorobutanesulfonate Exposure Causes Durable and Transgenerational Dysbiosis of Gut Microbiota in Marine Medaka](https://gwf-uwaterloo.github.io/gwf-publications/G18-29001) (Chen et al., GWF 2018)
ACL
- Lianguo Chen, James C.W. Lam, Chenyan Hu, Mirabelle M.P. Tsui, Qi Wang, John P. Giesy, and Paul K.S. Lam. 2018. Perfluorobutanesulfonate Exposure Causes Durable and Transgenerational Dysbiosis of Gut Microbiota in Marine Medaka. Environmental Science & Technology Letters, Volume 5, Issue 12, 5(12):731–738.
