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        <title>A Microflow Cytometry-Based Agglutination Immunoassay for Point-of-Care Quantitative Detection of SARS-CoV-2 IgM and IgG</title>
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    <name type="personal">
        <namePart type="given">Jianxi</namePart>
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    <name type="personal">
        <namePart type="given">Mathieu</namePart>
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    <name type="personal">
        <namePart type="given">Yushan</namePart>
        <namePart type="family">Zhang</namePart>
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    <name type="personal">
        <namePart type="given">Chang‐Qing</namePart>
        <namePart type="family">Xu</namePart>
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            <title>Micromachines, Volume 12, Issue 4</title>
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            <publisher>MDPI AG</publisher>
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    <abstract>A rapid, sensitive and simple microflow cytometry-based agglutination immunoassay (MCIA) was developed for point-of-care (POC) quantitative detection of SARS-CoV-2 IgM and IgG antibodies. The antibody concentration was determined by using the transit time of beads aggregates. A linear relationship was established between the average transit time and the concentration of SARS-CoV-2 IgM and IgG, respectively. The limit of detection (LOD) of SARS-CoV-2 IgM and IgG by the MCIA measurement are 0.06 mg/L and 0.10 mg/L, respectively. The 10 μL sample consumption, 30 min assay time and the compact setup make this technique suitable for POC quantitative detection of SARS-CoV-2 antibodies.</abstract>
    <identifier type="citekey">Qu-2021-A</identifier>
    <identifier type="doi">10.3390/mi12040433</identifier>
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        <url>https://gwf-uwaterloo.github.io/gwf-publications/G21-123001</url>
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    <part>
        <date>2021</date>
        <detail type="volume"><number>12</number></detail>
        <detail type="issue"><number>4</number></detail>
        <detail type="page"><number>433</number></detail>
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%0 Journal Article
%T A Microflow Cytometry-Based Agglutination Immunoassay for Point-of-Care Quantitative Detection of SARS-CoV-2 IgM and IgG
%A Qu, Jianxi
%A Chenier, Mathieu
%A Zhang, Yushan
%A Xu, Chang‐Qing
%J Micromachines, Volume 12, Issue 4
%D 2021
%V 12
%N 4
%I MDPI AG
%F Qu-2021-A
%X A rapid, sensitive and simple microflow cytometry-based agglutination immunoassay (MCIA) was developed for point-of-care (POC) quantitative detection of SARS-CoV-2 IgM and IgG antibodies. The antibody concentration was determined by using the transit time of beads aggregates. A linear relationship was established between the average transit time and the concentration of SARS-CoV-2 IgM and IgG, respectively. The limit of detection (LOD) of SARS-CoV-2 IgM and IgG by the MCIA measurement are 0.06 mg/L and 0.10 mg/L, respectively. The 10 μL sample consumption, 30 min assay time and the compact setup make this technique suitable for POC quantitative detection of SARS-CoV-2 antibodies.
%R 10.3390/mi12040433
%U https://gwf-uwaterloo.github.io/gwf-publications/G21-123001
%U https://doi.org/10.3390/mi12040433
%P 433

Markdown (Informal)

[A Microflow Cytometry-Based Agglutination Immunoassay for Point-of-Care Quantitative Detection of SARS-CoV-2 IgM and IgG](https://gwf-uwaterloo.github.io/gwf-publications/G21-123001) (Qu et al., GWF 2021)

• A Microflow Cytometry-Based Agglutination Immunoassay for Point-of-Care Quantitative Detection of SARS-CoV-2 IgM and IgG (Qu et al., GWF 2021)

ACL

• Jianxi Qu, Mathieu Chenier, Yushan Zhang, and Chang‐Qing Xu. 2021. A Microflow Cytometry-Based Agglutination Immunoassay for Point-of-Care Quantitative Detection of SARS-CoV-2 IgM and IgG. Micromachines, Volume 12, Issue 4, 12(4):433.