Process-based modelling offers interpretability and physical consistency in many domains of geosciences but struggles to leverage large datasets efficiently. Machine-learning methods, especially deep networks, have strong predictive skills yet are unable to answer specific scientific questions. In this Perspective, we explore differentiable modelling as a pathway to dissolve the perceived barrier between process-based modelling and machine learning in the geosciences and demonstrate its potential with examples from hydrological modelling. ‘Differentiable’ refers to accurately and efficiently calculating gradients with respect to model variables or parameters, enabling the discovery of high-dimensional unknown relationships. Differentiable modelling involves connecting (flexible amounts of) prior physical knowledge to neural networks, pushing the boundary of physics-informed machine learning. It offers better interpretability, generalizability, and extrapolation capabilities than purely data-driven machine learning, achieving a similar level of accuracy while requiring less training data. Additionally, the performance and efficiency of differentiable models scale well with increasing data volumes. Under data-scarce scenarios, differentiable models have outperformed machine-learning models in producing short-term dynamics and decadal-scale trends owing to the imposed physical constraints. Differentiable modelling approaches are primed to enable geoscientists to ask questions, test hypotheses, and discover unrecognized physical relationships. Future work should address computational challenges, reduce uncertainty, and verify the physical significance of outputs. Differentiable modelling is an approach that flexibly integrates the learning capability of machine learning with the interpretability of process-based models. This Perspective highlights the potential of differentiable modelling to improve the representation of processes, parameter estimation, and predictive accuracy in the geosciences.

Global Institute for Water Security, University of Saskatchewan, Saskatoon, Saskatchewan, Canada School of Geosciences, University of Birmingham, Birmingham, UK Dept of Earth, Ocean & Atmospheric Sciences, University of British Columbia, Vancouver, British Columbia, Canada Landcare Research, Lincoln, New Zealand Swiss Federal Institute of Aquatic Science and Technology, Dübendorf, Switzerland Centre for Hydrology, University of Saskatchewan, Canmore, Alberta, Canada School of Geographical Sciences, University of Bristol, Bristol, UK Cabot Institute, University of Bristol, Bristol, UK Hetch Hetchy Power, San Francisco, California, USA Division of Earth and Ocean Sciences, Nicolas School of the Environment, Duke University, Durham, North Carolina, USA GNS Science, Lower Hutt, New Zealand Department of Civil Engineering, Univeristy of Calgary, Calgary, Alberta, Canada Disaster Prevention Research Institute, Kyoto University, Kyoto, Japan Department of Geography, University of Zurich, Zurich, Switzerland Dept of Biological and Ecological Engineering, Oregon State University, Corvallis, Oregon, USA Faculty of Environment & Natural Resources, University of Freiburg, Freiburg, Germany Faculty of Engineering, University of Bristol, Bristol, UK