Chemical Communications, Volume 57, Issue 62


Anthology ID:
G21-124
Month:
Year:
2021
Address:
Venue:
GWF
SIG:
Publisher:
Royal Society of Chemistry (RSC)
URL:
https://gwf-uwaterloo.github.io/gwf-publications/G21-124
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Selection of a self-cleaving ribozyme activated in a chemically and thermally denaturing environment
Lingzi Ma | Zhicheng Huang | Juewen Liu | Lingzi Ma | Zhicheng Huang | Juewen Liu

A self-cleaving ribozyme was obtained from <italic>in vitro</italic> selection, displaying site-specific cleavage activity under various denaturing conditions, such as high temperatures, 20 M formamide, and low salt concentrations.